Symptom Finder - Treatment of Pyelonephritis
PYELONEPHRITIS
1. Force clear liquid p.o. Generous IV fluids in hospitalized patients.
2. Ciprofloxacin (Cipro): 500 mg bid × 10 days. Alternatively may use other quinolones:
3. Patients who cannot tolerate quinolones may be given cefuroxime (Ceftin) 500 mg bid.
4. Patients who are severely ill may be hospitalized and treated with cefazolin (Kefzol) 1 g IV q12hrs along with tobramycin (Nebcin) 125 mg/kg per dose q8hrs. Alternatively levofloxacin (Levaquin) 750 mg IV daily may be given.
5. More specific antibiotic therapy can be given once cultures and sensitivities are back.
6. Consult an urologist to evaluate for obstructive uropathy and other lesions that may contribute to pyelonephritis.
7. Treat pain with morphine 2.5–15 mg IV or IM q2–4hrs PRN.
8. Treat nausea and vomiting with trimethobenzamide (Tigan) suppositories 200 mg q8hrs. PRN or ondansetron (Zofran) 2–4 mg IV q4hrs PRN.
1. Force clear liquid p.o. Generous IV fluids in hospitalized patients.
2. Ciprofloxacin (Cipro): 500 mg bid × 10 days. Alternatively may use other quinolones:
3. Patients who cannot tolerate quinolones may be given cefuroxime (Ceftin) 500 mg bid.
4. Patients who are severely ill may be hospitalized and treated with cefazolin (Kefzol) 1 g IV q12hrs along with tobramycin (Nebcin) 125 mg/kg per dose q8hrs. Alternatively levofloxacin (Levaquin) 750 mg IV daily may be given.
5. More specific antibiotic therapy can be given once cultures and sensitivities are back.
6. Consult an urologist to evaluate for obstructive uropathy and other lesions that may contribute to pyelonephritis.
7. Treat pain with morphine 2.5–15 mg IV or IM q2–4hrs PRN.
8. Treat nausea and vomiting with trimethobenzamide (Tigan) suppositories 200 mg q8hrs. PRN or ondansetron (Zofran) 2–4 mg IV q4hrs PRN.