Pathology Definition -What are the signs of irreversible cell injury?
What are the signs of irreversible cell injury?
Initially, the differences between the reversible and irreversible cell injury are only quantitative. For example, the hypoxic vacuoles become more numerous and larger. The mitochondria are swollen, and many are even ruptured. However, many of these changes are still reversible, and it
is only when the plasma membrane ruptures and the nuclear changes ensue that one can be certain that an injury is irreversible and the cell is dead.
Initially, the differences between the reversible and irreversible cell injury are only quantitative. For example, the hypoxic vacuoles become more numerous and larger. The mitochondria are swollen, and many are even ruptured. However, many of these changes are still reversible, and it
is only when the plasma membrane ruptures and the nuclear changes ensue that one can be certain that an injury is irreversible and the cell is dead.
