Pharmacology definition - Propylthiouracil
Propylthiouracil
Propylthiouracil is a type of drug which inhibits the synthesis of thyroid hormone in the thyroid gland. Propylthiouracil will inhibit the conversion of T4 to T3 peripherally. Propylthiouracil will inhibit the enzyme thyroid peroxidase which is useful in organification of the iodine. Propylthiouracil may also inhibit the iodotyrosines coupling.
The common side effects of propylthiouracil may include arthralgia, maculopapular skin rash and agranulocytosis.
Propylthiouracil is also known as methimazole which is useful as a medication to treat hyperthyroidism.
Propylthiouracil is a type of drug which inhibits the synthesis of thyroid hormone in the thyroid gland. Propylthiouracil will inhibit the conversion of T4 to T3 peripherally. Propylthiouracil will inhibit the enzyme thyroid peroxidase which is useful in organification of the iodine. Propylthiouracil may also inhibit the iodotyrosines coupling.
The common side effects of propylthiouracil may include arthralgia, maculopapular skin rash and agranulocytosis.
Propylthiouracil is also known as methimazole which is useful as a medication to treat hyperthyroidism.
