Pathology Definition -What are myelin figures?
What are myelin figures?
Myelin figures are cytoplasmic bodies seen in damaged cells by electron microscopy. They are composed of concentric whorls of membranes derived from damaged cytoplasmic organelles, such as mitochondria, or RER. Myelin figures are prominent in neurons in Tay-Sachs disease
and other inborn errors of metabolism damaging the cytoplasmic membranes. Like other
remnants of damaged organelles, myelin figures are taken up into autophagosomes.
Myelin figures are cytoplasmic bodies seen in damaged cells by electron microscopy. They are composed of concentric whorls of membranes derived from damaged cytoplasmic organelles, such as mitochondria, or RER. Myelin figures are prominent in neurons in Tay-Sachs disease
and other inborn errors of metabolism damaging the cytoplasmic membranes. Like other
remnants of damaged organelles, myelin figures are taken up into autophagosomes.