Infectious Disease definition - Infant Diarrhea

Infant diarrhea
Infant diarrhea/watery diarrhea commonly affecting infant mostly in an underdeveloped countries and presented with symptoms and signs such as vomiting and diarrhea.
Common microrganisms causing infant diarrhea are Enteroaggregative Escherichia coli and Enteropathogenic Escherichia coli. Both of these microorganisms are gram negative rod. Enteroaggregative E.coli carries an invasion and enterotoxin types of virulence mechanism. Enteroaggregative E. coli will lead to formation of mucus biofilm and large aggregate which will block any absorption of enterocytes of the small intestine. As a consequences this will lead to watery diarrhea. Enteropathogenic E. coli carries an invasion, endotoxin and heat stable enterotoxin virulence mechanism. The Enteropathogenic E. coli will attach to the enterocytes of the small intestine and leads to stimulation of an actin rearrangement of the host cell. This will lead to the formation of the pedestal, decreased absorption of the fluid and destruction of the microvilli .
Infant diarrhea is a self limiting illness which is treated with symptomatic/supportive therapy such as fluid and electrolytes replacement therapy.
References
1.Levine, MYRON M., and R. O. B. E. R. T. Edelman. "Enteropathogenic Escherichia coli of classic serotypes associated with infant diarrhea: epidemiology and pathogenesis." Epidemiologic reviews 6 (1983): 31-51.
2.Clausen, Carla R., and Dennis L. Christie. "Chronic diarrhea in infants caused by adherent enteropathogenic< i> Escherichia coli</i>." The Journal of pediatrics 100.3 (1982): 358-361.
Infant diarrhea/watery diarrhea commonly affecting infant mostly in an underdeveloped countries and presented with symptoms and signs such as vomiting and diarrhea.
Common microrganisms causing infant diarrhea are Enteroaggregative Escherichia coli and Enteropathogenic Escherichia coli. Both of these microorganisms are gram negative rod. Enteroaggregative E.coli carries an invasion and enterotoxin types of virulence mechanism. Enteroaggregative E. coli will lead to formation of mucus biofilm and large aggregate which will block any absorption of enterocytes of the small intestine. As a consequences this will lead to watery diarrhea. Enteropathogenic E. coli carries an invasion, endotoxin and heat stable enterotoxin virulence mechanism. The Enteropathogenic E. coli will attach to the enterocytes of the small intestine and leads to stimulation of an actin rearrangement of the host cell. This will lead to the formation of the pedestal, decreased absorption of the fluid and destruction of the microvilli .
Infant diarrhea is a self limiting illness which is treated with symptomatic/supportive therapy such as fluid and electrolytes replacement therapy.
References
1.Levine, MYRON M., and R. O. B. E. R. T. Edelman. "Enteropathogenic Escherichia coli of classic serotypes associated with infant diarrhea: epidemiology and pathogenesis." Epidemiologic reviews 6 (1983): 31-51.
2.Clausen, Carla R., and Dennis L. Christie. "Chronic diarrhea in infants caused by adherent enteropathogenic< i> Escherichia coli</i>." The Journal of pediatrics 100.3 (1982): 358-361.