Surgery Definition – What is duodenal ulcer?
Surgery Definition – What is duodenal ulcer?
Duodenal ulcer is a form of peptic ulcer which affects people within the age of 40 – 65. The cause of duodenal ulcer is Helicobacter pylori. The risk factors of developing duodenal ulcer are smoking, NSAIDS intake, male, sufferer of Zollinger Ellison syndrome, hypercalcemic status, chronic renal failure, familial causes, hyper parathyroidism, chronic obstructive pulmonary disease and alcoholic cirrhosis. Patient with duodenal ulcer may present with epigastric pain mostly at night time, vomiting, nausea, hematemesis and melaena stool. The epigastric pain is relived by eating. There will be tenderness in the epigastrium region.
Duodenal ulcer is caused by increase in the production of gastric acid mostly in the case of hypercalcemia as calcium will stimulates the gastrin production. Duodenal ulcer mostly occurs within 2 cm of the pylorus in the bulb of the duodenum. The investigation requires include esophagogastroduodenoscopy which is the gold standard. The biopsy is later performed at the edge of the ulcer. Helicobacter pylori is detected by the detection of the blood for antibodies, urea breath test where the H. pylori producing urease which split the urea and releasing ammonia, clo test on the mucosal biopsy and microscopy analysis of the biopsy taken from the organisms.
The treatment of duodenal ulcer may include symptomatic treatment and antibiotic for helicobacter pylori. The treatment may include the CMO regime which include the clarithromycin, metronidazole and omeprazole. In another words two forms of antibiotics and a proton pump inhibitor. This will follow with continuation of the usage of the proton pump inhibitors or H2 blockers.
The surgical treatment may consider in the case of failure in medical therapy, due to the formation of gastric cancer, hemorrhage, gastric outlet obstruction due to scarring or stricture or perforation. The aim of the surgical treatment is to divide the vagus nerve with the aim to reduce the secretion of the acid. The procedure includes selective vagotomy and pyloroplasty, truncal vagotomy and pyloroplasty and highly selective vagotomy.
Duodenal ulcer is a form of peptic ulcer which affects people within the age of 40 – 65. The cause of duodenal ulcer is Helicobacter pylori. The risk factors of developing duodenal ulcer are smoking, NSAIDS intake, male, sufferer of Zollinger Ellison syndrome, hypercalcemic status, chronic renal failure, familial causes, hyper parathyroidism, chronic obstructive pulmonary disease and alcoholic cirrhosis. Patient with duodenal ulcer may present with epigastric pain mostly at night time, vomiting, nausea, hematemesis and melaena stool. The epigastric pain is relived by eating. There will be tenderness in the epigastrium region.
Duodenal ulcer is caused by increase in the production of gastric acid mostly in the case of hypercalcemia as calcium will stimulates the gastrin production. Duodenal ulcer mostly occurs within 2 cm of the pylorus in the bulb of the duodenum. The investigation requires include esophagogastroduodenoscopy which is the gold standard. The biopsy is later performed at the edge of the ulcer. Helicobacter pylori is detected by the detection of the blood for antibodies, urea breath test where the H. pylori producing urease which split the urea and releasing ammonia, clo test on the mucosal biopsy and microscopy analysis of the biopsy taken from the organisms.
The treatment of duodenal ulcer may include symptomatic treatment and antibiotic for helicobacter pylori. The treatment may include the CMO regime which include the clarithromycin, metronidazole and omeprazole. In another words two forms of antibiotics and a proton pump inhibitor. This will follow with continuation of the usage of the proton pump inhibitors or H2 blockers.
The surgical treatment may consider in the case of failure in medical therapy, due to the formation of gastric cancer, hemorrhage, gastric outlet obstruction due to scarring or stricture or perforation. The aim of the surgical treatment is to divide the vagus nerve with the aim to reduce the secretion of the acid. The procedure includes selective vagotomy and pyloroplasty, truncal vagotomy and pyloroplasty and highly selective vagotomy.