Pharmacology definition - Thiazolidinediones
Thiazolidinediones
Thiazolidinediones are useful in treating patient with non insulin dependent type 2 diabetes mellitus.
Thiazolidinediones are useful in decreasing the insulin resistance which decrease the level of the serum glucose. There will be an increase in the uptake of glucose by the fat cells and muscle cells. Thiazolidinediones may inhibit the hepatic gluconeogenesis.
Thiazolidinediones may include troglitazone and pioglitazone. Troglitazone may be harmful in patient with hepatic failure due to troglitazone hepatotoxicity. Thiazolidinediones may carry the side effects such as edema, hypoglycemia and anemia. Patient is required to perform the liver function test before and while using thiazolidinediones ( troglitazone).
Thiazolidinediones are useful in treating patient with non insulin dependent type 2 diabetes mellitus.
Thiazolidinediones are useful in decreasing the insulin resistance which decrease the level of the serum glucose. There will be an increase in the uptake of glucose by the fat cells and muscle cells. Thiazolidinediones may inhibit the hepatic gluconeogenesis.
Thiazolidinediones may include troglitazone and pioglitazone. Troglitazone may be harmful in patient with hepatic failure due to troglitazone hepatotoxicity. Thiazolidinediones may carry the side effects such as edema, hypoglycemia and anemia. Patient is required to perform the liver function test before and while using thiazolidinediones ( troglitazone).
