What factors can affect the rate of rise of ventricular pressure?
The most important is contractility. An increase in left ventricular contractility (because of exogenous or endogenous inotropics) will intensify the mitral component of S1. Conversely, a decrease in
contractility (because of congestive heart failure) will soften it.
The most important is contractility. An increase in left ventricular contractility (because of exogenous or endogenous inotropics) will intensify the mitral component of S1. Conversely, a decrease in
contractility (because of congestive heart failure) will soften it.