Unclear. Early histology shows full-thickness epidermal necrosis, with little or no lymphocytic
infiltrate, suggesting that TEN is not induced by inflammation but by a cellular toxin, which is why
steroids and immunosuppressive therapy are not effective and, in fact, possibly detrimental.
infiltrate, suggesting that TEN is not induced by inflammation but by a cellular toxin, which is why
steroids and immunosuppressive therapy are not effective and, in fact, possibly detrimental.