Variable. Some patients rapidly lose large areas of the skin in just a few days, whereas others begin reepithelialization almost as quickly. Predicting the course at initial presentation is not possible. Overall,
re-epithelialization is usually complete within 3 weeks, but pressure and mucosal areas may remain eroded andcrusted for 2 weeks or longer. Long-term sequelae of Stevens Johnson Syndrome /Toxic epidermal Necrolysis vary based on site:Disabling eye lesions may cause blindness in 40% of TEN survivors. Persistent watery eyes or a sicca-like syndrome can also occur.
Cutaneous lesions may resolve with a mottling of hyperpigmentation and hypopigmentation.
Genitourinary lesions may result in phimosis or vaginal synechiae.
Fingernails and toenails may regrow abnormally.
re-epithelialization is usually complete within 3 weeks, but pressure and mucosal areas may remain eroded andcrusted for 2 weeks or longer. Long-term sequelae of Stevens Johnson Syndrome /Toxic epidermal Necrolysis vary based on site:Disabling eye lesions may cause blindness in 40% of TEN survivors. Persistent watery eyes or a sicca-like syndrome can also occur.
Cutaneous lesions may resolve with a mottling of hyperpigmentation and hypopigmentation.
Genitourinary lesions may result in phimosis or vaginal synechiae.
Fingernails and toenails may regrow abnormally.