Because hyperinsulinemia activates 11-Betahydroxysteroid dehydrogenase in omental adipose
tissue, thus generating active cortisol and promoting a cushingoid fat distribution. Hence, WC is an excellent
tool to either exclude insulin resistance or identify subjects at risk.
tissue, thus generating active cortisol and promoting a cushingoid fat distribution. Hence, WC is an excellent
tool to either exclude insulin resistance or identify subjects at risk.