1. Hereditary angioedema: Autosomal dominant, it presents in the second to fourth decade of life with
sudden attacks of angioedema that often last for days and can be life threatening. Due to low or nonfunctional C1 inhibitor, with diagnosis being suggested by a low C4 level.
2. Physical urticarias: appear in response to a stimulus, such as cold, sunlight, trauma, water:
Dermatographism (wheals at site of skinstroking)
Pressure urticaria (severe swelling with deep pain several hours after localized pressure is applied, most commonly on feet and buttocks)
Aquagenic urticaria (elicited by water, as in a cold or hot shower)
Cold urticaria (from rewarming of skin exposed to cold; most common on hands and feet)
Solar urticaria (urticaria on unshielded skin after exposure to sunlight)
Cholinergic urticaria (on face and trunk, pruritusi nduced by exercise and emotional stress)
sudden attacks of angioedema that often last for days and can be life threatening. Due to low or nonfunctional C1 inhibitor, with diagnosis being suggested by a low C4 level.
2. Physical urticarias: appear in response to a stimulus, such as cold, sunlight, trauma, water:
Dermatographism (wheals at site of skinstroking)
Pressure urticaria (severe swelling with deep pain several hours after localized pressure is applied, most commonly on feet and buttocks)
Aquagenic urticaria (elicited by water, as in a cold or hot shower)
Cold urticaria (from rewarming of skin exposed to cold; most common on hands and feet)
Solar urticaria (urticaria on unshielded skin after exposure to sunlight)
Cholinergic urticaria (on face and trunk, pruritusi nduced by exercise and emotional stress)